SCHEMBL17754688

SCHEMBL17754688

c1ccc([Si](c2ccccc2)(c2ccc(-c3ccc([Si](c4ccccc4)(c4ccccc4)c4cccc(-c5nccc6c5sc5ccccc56)c4)cc3)cc2)c2cccc(-c3cccc4c3sc3ccccc34)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.47
PRKDC P78527 2/20 0.37
TDO2 P48775 7/20 0.34
DNPH1 O43598 1/20 0.34
LIMK1 P53667 4/20 0.33
PARP14 Q460N5 1/20 0.33
IDO1 P14902 1/20 0.32
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
HTR2B P41595 2/20 0.32
HTR5A P47898 2/20 0.32
BCHE P06276 1/20 0.31
PIM3 Q86V86 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17754697 0.98 ALOX5 (0.46) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL17754693 0.94 ALOX5 (0.43) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL17754685 0.94 ALOX5 (0.43) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL26238249 0.91 TNKS (0.37) ALOX5TDO2LIMK1IDO1TNKS
SCHEMBL17754643 0.90 ALOX5 (0.57) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL17754690 0.89 ALOX5 (0.43) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL14948276 0.88 TNKS (0.34) ALOX5TDO2LIMK1IDO1TNKS
SCHEMBL17754687 0.88 ALOX5 (0.38) ALOX5PRKDCTDO2DNPH1
SCHEMBL17754638 0.87 ALOX5 (0.56) ALOX5PRKDCTDO2DNPH1LIMK1
SCHEMBL13681149 0.86 ALOX5 (0.52) ALOX5PRKDCLIMK1PARP14TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9761814-B2 Organic light-emitting materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-09-12 US disclosed
US-9761814-B2 Organic light-emitting materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-09-12 US disclosed
US-20160141525-A1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160141525-A1 ORGANIC LIGHT-EMITTING MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBPL3 ALOX5 234/4885PRKDC 3373/4885TDO2 893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.