Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115376 | 0.76 | HPGD (0.34) | HPGD | |
| SCHEMBL620772 | 0.75 | — | — | |
| Water SCHEMBL542921 | 0.72 | — | — | |
| SCHEMBL28987617 | 0.72 | — | — | |
| Acetone SCHEMBL28144848 | 0.63 | CES2 (0.37) | — | |
| SCHEMBL16370920 | 0.61 | CES2 (0.35) | — | |
| SCHEMBL23581763 | 0.60 | DAO (0.50) | HPGD | |
| SCHEMBL8635819 | 0.59 | GSK3B (0.58) | HPGD | |
| SCHEMBL1953538 | 0.57 | KMT2A (0.64) | HPGD | |
| SCHEMBL2171289 | 0.57 | CES2 (0.34) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943600-B2 | Antimicrobial combination therapy | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20060193924-A1 | Antimicrobial combination therapy | NATIONAL INSTITUTES OF HEALTH | 2006-08-31 | — | — | US | disclosed |
| WO-2006071685-A2 | ANTIMICROBIAL COMBINATION THERAPY COMPRISING AN ANTIBIOTIC AND TOXIC COMPOUND SELECTED FROM DNA DAMAGING AGENTS, ALKYLATING AGENTS, HEAVY METAL CONTAINING COMPOUNDS AND CHELATING AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-07-06 | — | — | WO | disclosed |