Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775901 | 0.99 | HTR6 (0.44) | HTR6HTR2CHTTNMT1NCF1 | |
| SCHEMBL6385040 | 0.96 | HTR6 (0.47) | HTR6HTR2CHTTNCF1HTR1D | |
| SCHEMBL1775896 | 0.90 | HTR6 (0.53) | HTR6HTR2C | |
| Hydrochloric Acid SCHEMBL1773925 | 0.89 | HTR6 (0.52) | HTR6HTR2C | |
| SCHEMBL6382957 | 0.89 | HTR6 (0.47) | HTR6HTR2C | |
| SCHEMBL1775121 | 0.87 | HTR6 (0.45) | HTR6HTR2CNMT1PRKCIHTR1D | |
| Hydrochloric Acid SCHEMBL1776341 | 0.87 | HTR6 (0.44) | HTR6HTR2CNMT1PRKCIHTR1D | |
| SCHEMBL1776454 | 0.86 | HTR6 (0.50) | HTR6HTR2CNMT1PRKCI | |
| SCHEMBL1776393 | 0.86 | HTR6 (0.46) | HTR6HTR2CNMT1PRKCICHRNB2 | |
| Hydrochloric Acid SCHEMBL1775284 | 0.85 | HTR6 (0.49) | HTR6HTR2CNMT1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |