SCHEMBL1775656

SCHEMBL1775656

C=CCO[C@H]1O[C@H](COCc2ccccc2)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](OCc3ccccc3)[C@H](OCc3ccccc3)[C@H]2OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 10/20 0.48
▸ CDC25B P30305 8/20 0.48
▸ PTPN2 P17706 5/20 0.47
▸ PTPN11 Q06124 5/20 0.47
▸ PTPN6 P29350 4/20 0.46
▸ NT5E P21589 1/20 0.46
▸ SLC6A2 P23975 1/20 0.45
▸ SSTR1 P30872 1/20 0.45
▸ SSTR2 P30874 1/20 0.45
▸ SSTR4 P31391 1/20 0.45
▸ SSTR3 P32745 1/20 0.45
▸ SSTR5 P35346 1/20 0.45
▸ GJB2 P29033 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1776554 1.00 PTPN1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL1775653 1.00 PTPN1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL1776776 0.96 SSTR1 (0.45) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL8928604 0.95 SSTR1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL9167095 0.95 SSTR1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL1775256 0.95 SSTR1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL1775254 0.95 SSTR1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL13038862 0.95 SSTR1 (0.48) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL1776774 0.94 SLC6A2 (0.47) PTPN1CDC25BPTPN2PTPN11PTPN6
SCHEMBL14876616 0.93 SLC6A2 (0.49) PTPN1CDC25BPTPN2PTPN11PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943584-B2 Medicinal composition containing diabetes remedy SANKYO COMPANY, LIMITED (JP) 2011-05-17 — — US disclosed
EP-1589023-B1 OLIGOSACCHARIDE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2010-08-25 — — EP disclosed
US-7632930-B2 Oligosaccharide derivative SANKYO COMPANY LIMITED (JP) 2009-12-15 — — US disclosed
US-20080194495-A1 Oligosaccharide Derivative HONDA TAKESHI 2008-08-14 — — US disclosed
US-7361744-B2 Oligosaccharide derivative SANKYO COMPANY LIMITED (JP) 2008-04-22 — — US disclosed
US-20080039367-A1 Medicinal Composition Containing Diabeted Remedy SANKYO COMPANY, LIMITED (JP) 2008-02-14 — — US disclosed
EP-1792620-A1 MEDICINAL COMPOSITION CONTAINING DIABETES REMEDY Sankyo Company, Limited (JP) 2007-06-06 — — EP disclosed
US-20060025350-A1 Oligosaccharide derivative SANKYO COMPANY, LIMITED (JP) 2006-02-02 — — US disclosed
EP-1589023-A1 OLIGOSACCHARIDE DERIVATIVE Sankyo Company, Limited (JP) 2005-10-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039367-A1 Medicinal Composition Containing Diabeted Remedy DPP4, IAPP, AMY2A PTPN1 175/4885CDC25B 2720/4885PTPN2 343/4885
US-20060025350-A1 Oligosaccharide derivative MAN1B1, FUT6, MAN2A1 PTPN1 1359/4885CDC25B 1997/4885PTPN2 1866/4885
US-20080194495-A1 Oligosaccharide Derivative MAN1B1, FUT6, MAN2A1 PTPN1 1359/4885CDC25B 1997/4885PTPN2 1866/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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