SCHEMBL177572

SCHEMBL177572

O=Cc1coc2ccc(Br)cc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 10/20 1.00
PTPN2 P17706 1/20 0.61
MAOA P21397 9/20 0.60
MAOB P27338 9/20 0.60
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
POLB P06746 1/20 0.56
GAA P10253 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
RECQL P46063 1/20 0.56
KMT2A Q03164 1/20 0.56
HTT P42858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15951253 0.88 PTPN1 (0.78) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL29529294 0.87 PTPN1 (0.77) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL19182133 0.87 PTPN1 (0.77) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL7025065 0.83 PTPN1 (0.70) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL28318700 0.81 ALDH1A1 (0.70) PTPN1MAOAMAOBMEN1ALDH1A1
SCHEMBL23707495 0.80 PTPN1 (0.67) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL12174817 0.80 PTPN1 (0.67) PTPN1PTPN2MAOAMAOBALDH1A1
SCHEMBL911098 0.80 ALDH1A1 (0.68) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL29951299 0.80 PTPN1 (1.00) PTPN1PTPN2MAOAMAOBMEN1
SCHEMBL29952420 0.80 ALDH1A1 (0.68) PTPN1PTPN2MAOAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117466915-A Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof 江西科技师范大学 2024-01-30 CN claimed
CN-117285925-A Ratio fluorescence and colorimetric dual-mode reagent for detecting ethylenediamine based on electron energy transfer mechanism 中国科学院新疆理化技术研究所 2023-12-26 CN claimed
CN-114790213-A Synthetic method of spiro [ indazole-isoxazole ] derivative applied to methoxyphenyl substituted chromone-containing structure 徐诺药业(南京)有限公司 2022-07-26 CN claimed
CN-110143971-B Methylthiophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2021-04-30 CN claimed
CN-110128446-B 3,4, 5-trimethoxy phenyl substituted spiro [ indazole-isoxazole ] derivative containing chromone structure, and preparation method and application thereof 绍兴文理学院 2021-02-09 CN claimed
CN-110183467-B P-methoxyphenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2020-12-08 CN claimed
CN-110128445-B P-chlorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2020-12-08 CN claimed
CN-110256462-B Para-fluorophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2020-11-13 CN claimed
CN-110128447-B P-methylphenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2020-11-13 CN claimed
CN-110128444-B P-nitrophenyl substituted chromone structure-containing spiro [ indazole-isoxazole ] derivative, and preparation method and application thereof 绍兴文理学院 2020-11-13 CN claimed
CN-110156812-B Spiro [ indazole-isoxazole ] derivative containing chromone structure, and preparation method and application thereof 绍兴文理学院 2020-09-11 CN claimed
CN-119977949-A Chromone bisindole derivative and preparation method and application thereof 重庆文理学院 2025-05-13 CN disclosed
CN-119930565-A Hydroxy flavonoid derivative and preparation method and application thereof 重庆文理学院 2025-05-06 CN disclosed
CN-117466915-A Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof 江西科技师范大学 2024-01-30 CN disclosed
EP-4306106-A1 NITRO-CONTAINING COMPOUNDS, COMPOSITIONS AND USES THEREOF Universidade de Aveiro (PT) 2024-01-17 EP disclosed
EP-0695753-A1 Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use ZENECA LIMITED (GB) 1996-02-07 EP disclosed
US-4320133-A Penicillins and their antibacterial use SANDOZ LTD. (CH) 1982-03-16 US disclosed
US-4098799-A ANTIALLERGENS, HYPERACIDITY WARNER-LAMBERT COMPANY (US) 1978-07-04 US disclosed
US-4008252-A ANTIALLERGENS, ANTIHYPERACIDITY WARNER-LAMBERT COMPANY (US) 1977-02-15 US disclosed
US-3937837-A SUBSTITUTED CHROMONE-3-CARBONITRILES, CARBOXAMIDES AND CARBOXYLIC ACIDS USEFUL FOR PREVENTING ASTHMATIC SYMPTOMS WARNER-LAMBERT COMPANY (US) 1976-02-10 US disclosed