Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 11/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914271 | 0.82 | BCHE (0.43) | AGTR2ABHD6DAGLA | |
| SCHEMBL1775754 | 0.72 | KLK7 (0.44) | AGTR2 | |
| SCHEMBL1776891 | 0.72 | KLK7 (0.44) | AGTR2 | |
| SCHEMBL18587328 | 0.69 | AGTR2 (0.47) | AGTR2ABHD6DAGLA | |
| SCHEMBL6975692 | 0.68 | AGTR2 (0.46) | AGTR2ABHD6OPRM1OPRD1OPRK1 | |
| SCHEMBL22555190 | 0.68 | AGTR2 (0.46) | AGTR2ABHD6OPRM1OPRD1OPRK1 | |
| SCHEMBL4297034 | 0.68 | AGTR2 (0.46) | AGTR2ABHD6OPRM1OPRD1OPRK1 | |
| SCHEMBL18588189 | 0.67 | AGTR2 (0.46) | AGTR2ABHD6DAGLA | |
| SCHEMBL20484804 | 0.67 | AGTR2 (0.46) | AGTR2ABHD6DAGLA | |
| SCHEMBL5465300 | 0.66 | AGTR2 (0.40) | AGTR2ABHD6DAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943584-B2 | Medicinal composition containing diabetes remedy | SANKYO COMPANY, LIMITED (JP) | 2011-05-17 | — | — | US | disclosed |