Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27571305 | 1.00 | CA12 (0.42) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL219249 | 0.92 | CA12 (0.50) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL486710 | 0.90 | CA12 (0.52) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL27478117 | 0.88 | CA12 (0.55) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL887189 | 0.88 | CA12 (0.55) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL6009739 | 0.86 | CA12 (0.52) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL2382227 | 0.82 | CA12 (0.44) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL1525247 | 0.81 | CA12 (0.65) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL7096499 | 0.79 | CA12 (0.55) | CA12CA2CA3CA9CA14 | |
| Phenol SCHEMBL27361058 | 0.79 | CA12 (0.37) | CA12CA2CA3CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075598-A | Methods for identifying a medical condition in a human subject | 23吉盖私人有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-118251502-A | Method for judging risk of adverse event | 株式会社益力多本社 | 2024-06-25 | — | — | CN | disclosed |
| CN-111148834-B | Method for isolating RNA in high yield | 凯杰有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2024089293-A1 | MIR-326 FOR THE TREATMENT OF CANCER | FUNDACIÓN PARA LA INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL UNIVERSITARIO RAMÓN Y CAJAL (ES) | 2024-05-02 | — | — | WO | disclosed |
| EP-4360657-A1 | MIR-326 FOR THE TREATMENT OF CANCER | Fundación para la Investigación Biomédica del Hospital Universitario Ramón y Cajal (ES) | 2024-05-01 | — | — | EP | disclosed |
| CN-117413069-A | Internal standard gene of skin surface lipid sample | 花王株式会社 | 2024-01-16 | — | — | CN | disclosed |
| CN-110511924-B | Isolation of micrornas from biological fluids | 西格马-奥尔德里奇有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116848265-A | Method for preparing nucleic acid sample from skin stratum corneum | 花王株式会社 | 2023-10-03 | — | — | CN | disclosed |
| CN-116801885-A | RNAi agents for inhibiting DUX4 expression, compositions and methods of use | 箭头药业股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116635526-A | Method for detecting severe degree of atopic dermatitis | 花王株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-1216994-A | Apoptosis inducing molecule II | HUMAN GENOME SCIENCES INC (US) | 1999-05-19 | — | — | CN | disclosed |
| CN-1207771-A | Methods and compositions for diagnosis and treatment of tumors | UNIV TEXAS (US) | 1999-02-10 | — | — | CN | disclosed |
| US-5861502-A | FOR TREATING GENETIC COLLAGEN DISORDERS BY SELECTIVE SUPPRESSION OF PROTEIN EXPRESSION BY MUTATED GENES | THOMAS JEFFERSON UNIVERSITY (US) | 1999-01-19 | — | — | US | disclosed |
| CN-1196086-A | Enamel matrix related polypeptide | BIOLA AB (SE) | 1998-10-14 | — | — | CN | disclosed |
| CN-1190888-A | Methods and compositions for inhibiting 5 'alpha'=reductase activity | ARCH DEV CORP (US) | 1998-08-19 | — | — | CN | disclosed |
| CN-1187774-A | CNS neurite out growth modulators, and compositions, cells and methods embodying and using same | ACORDA THERAPEUTICS (US) | 1998-07-15 | — | — | CN | disclosed |
| EP-0674705-A1 | ANTISENSE OLIGONUCLEOTIDES TO INHIBIT EXPRESSION OF MUTATED AND WILD TYPE GENES FOR COLLAGEN | THOMAS JEFFERSON UNIVERSITY (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994011494-A1 | ANTISENSE OLIGONUCLEOTIDES TO INHIBIT EXPRESSION OF MUTATED AND WILD TYPE GENES FOR COLLAGEN | THOMAS JEFFERSON UNIVERSITY (US) | 1994-05-26 | — | — | WO | disclosed |
| EP-0550769-A1 | HEMATOPOIETIC STEM CELL MULTIPLIER | TORAY INDUSTRIES, INC. (JP) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992002529-A1 | EXPRESSION VECTORS REGULATED BY ESTROGEN AND A MUTANT ESTROGEN RECEPTOR | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1992-02-20 | — | — | WO | disclosed |