Phenol

Phenol

SCHEMBL27361058

ClC(Cl)Cl.N#CNC(=N)N.Oc1ccccc1.S

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
GLA P06280 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA9 Q16790 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA14 Q9ULX7 1/20 0.37
KMT2A Q03164 3/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
C1S P09871 1/20 0.33
PRSS3 P35030 1/20 0.33
RECQL P46063 1/20 0.33
ALDH1A1 P00352 2/20 0.33
USP2 O75604 1/20 0.33
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
F12 P00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL28244082 0.79 ALDH1A1 (0.47) GLATDP1KMT2APRSS1PRSS2
Phenol SCHEMBL177595 0.79 CA12 (0.42) CA12CA1CA2GLACA3
Phenol SCHEMBL27571305 0.79 CA12 (0.42) CA12CA1CA2GLACA3
Phenol SCHEMBL27478117 0.78 CA12 (0.55) CA12CA1CA2GLACA3
Phenol SCHEMBL887189 0.78 CA12 (0.55) CA12CA1CA2GLACA3
Benzene SCHEMBL28273853 0.78 KMT2A (0.33) KMT2APRSS1PRSS2C1SPRSS3
Phenol SCHEMBL6009739 0.76 CA12 (0.52) CA12CA1CA2GLACA3
Phenol SCHEMBL7096499 0.73 CA12 (0.55) CA12CA1CA2GLACA3
Phenol SCHEMBL2382227 0.73 CA12 (0.44) CA12CA1CA2GLACA3
Hydrogen Sulfide SCHEMBL22127086 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1062016-C Preparation of reorganized human saccharified urokinasen BIOLOG ENGINEERING I ACADEMY O (CN) 2001-02-14 CN claimed
CN-1178244-A Preparation of reorganized human saccharified urokinasen BIOLOG ENGINEERING I ACADEMY O (CN) 1998-04-08 CN claimed
CN-1651077-A New use of gene reconstituted urokin as origin TIANJIN TIANSHILI PHARMACEUTIC (CN) 2005-08-10 CN disclosed
CN-1062016-C Preparation of reorganized human saccharified urokinasen BIOLOG ENGINEERING I ACADEMY O (CN) 2001-02-14 CN disclosed
CN-1191491-A Connective tissue growth factor UNIV SOUTH FLORIDA (US) 1998-08-26 CN disclosed
CN-1178244-A Preparation of reorganized human saccharified urokinasen BIOLOG ENGINEERING I ACADEMY O (CN) 1998-04-08 CN disclosed