Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 8/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760018 | 0.90 | SIRT2 (0.36) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL22182348 | 0.89 | PDK2 (0.46) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL17759919 | 0.87 | ALDH1A1 (0.41) | PDK2MEN1KMT2APOLBALK | |
| SCHEMBL23765021 | 0.87 | MEN1 (0.39) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL17760154 | 0.86 | CDC25B (0.40) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL807849 | 0.85 | PDK2 (0.41) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL18212111 | 0.84 | PDK2 (0.39) | PDK2SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL19051121 | 0.84 | PDK2 (0.33) | PDK2MEN1KMT2APOLBALK | |
| SCHEMBL22920819 | 0.84 | PDK2 (0.43) | PDK2MEN1KMT2APOLBLMNA | |
| SCHEMBL18212129 | 0.84 | PDK2 (0.40) | PDK2SIRT2SIRT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016076629-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-05-19 | — | — | WO | disclosed |