Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21368218 | 0.92 | PDK2 (0.43) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL29767840 | 0.88 | PDK2 (0.44) | PDK2MEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL796163 | 0.88 | PDK2 (0.44) | PDK2MEN1KMT2ASIRT2SIRT1 | |
| SCHEMBL15183718 | 0.87 | PDK2 (0.44) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL29892218 | 0.86 | PDK2 (0.39) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL17050076 | 0.86 | ALDH1A1 (0.40) | PDK2HTTNPSR1RIPK2EGFR | |
| SCHEMBL807854 | 0.86 | PDK2 (0.39) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL15713467 | 0.86 | PDK2 (0.39) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL25657060 | 0.86 | PDK2 (0.49) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL17760045 | 0.85 | PDK2 (0.38) | PDK2MEN1APAF1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9947874-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-9947874-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| US-20160190447-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160190447-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-9312495-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| US-9312495-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| EP-2616428-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-12-24 | — | — | EP | disclosed |
| US-20130207046-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130207046-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| WO-2012034627-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160190447-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, EFNA1, EPCAM | PDK2 1024/4885MEN1 331/4885APAF1 3635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.