Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 2/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17759698 | 0.88 | PDK2 (0.39) | SIRT2SIRT1PDK2ALKAKR1C3 | |
| SCHEMBL17454691 | 0.86 | PDK2 (0.41) | PDK2ALKSTK10SLKPTGER4 | |
| SCHEMBL26277799 | 0.86 | PDK2 (0.34) | SIRT2SIRT1PDK2MEN1MAPT | |
| SCHEMBL29892218 | 0.85 | PDK2 (0.39) | SIRT2SIRT1PDK2PTGER4MAPKAPK2 | |
| SCHEMBL17759868 | 0.85 | PDK2 (0.36) | PDK2ALKSTK10SLKPTGER4 | |
| SCHEMBL15713467 | 0.85 | PDK2 (0.39) | SIRT2SIRT1PDK2PTGER4MAPKAPK2 | |
| SCHEMBL21615065 | 0.85 | PDK2 (0.44) | SIRT2SIRT1PDK2STK10SLK | |
| SCHEMBL17760018 | 0.85 | SIRT2 (0.36) | SIRT2SIRT1PDK2ALKAKR1C3 | |
| SCHEMBL17533320 | 0.85 | SIRT2 (0.34) | SIRT2SIRT1PDK2ALKAKR1C3 | |
| SCHEMBL23927563 | 0.84 | GAA (0.38) | SIRT2SIRT1PDK2ALKSTK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016076629-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-05-19 | — | — | WO | disclosed |