SCHEMBL17760145

SCHEMBL17760145

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4ccc(Nc5cccc6ccccc56)c(-c5ccccc5)c4)ccc3Nc3cccc(-c4ccccc4)c3)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ATM Q13315 1/20 0.41
HSD17B10 Q99714 1/20 0.41
FADS1 O60427 1/20 0.39
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
RAB9A P51151 1/20 0.34
CCR4 P51679 1/20 0.34
PDK2 Q15119 1/20 0.33
ABCG2 Q9UNQ0 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17760144 0.92 CDC25B (0.41) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL17760234 0.92 CDC25B (0.41) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL17759926 0.90 CDC25B (0.43) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL17759698 0.90 PDK2 (0.39) ATMSIRT2SIRT1RAB9APDK2
SCHEMBL17759523 0.88 ALDH1A1 (0.38) ALDH1A1CYP3A4HPGDHSD17B10SIRT2
SCHEMBL17760032 0.87 MAPT (0.40) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL22517548 0.86 ALDH1A1 (0.37) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL13367382 0.85 CDC25B (0.48) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL16366594 0.85 CDC25B (0.48) CDC25BALDH1A1TP53CYP3A4HPGD
SCHEMBL25125291 0.85 SIRT2 (0.40) SIRT2SIRT1PDK2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016076629-A1 A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2016-05-19 WO disclosed