Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | CALML3 | P27482 | 5/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SDHA | P31040 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096841 | 0.83 | MAOA (0.54) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393430 | 0.83 | MAOA (0.54) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393432 | 0.81 | MAOA (0.63) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10258340 | 0.80 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10197320 | 0.80 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL10197443 | 0.80 | MAOA (0.67) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393956 | 0.80 | MAOA (0.67) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14432626 | 0.80 | MAOA (0.66) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL11983108 | 0.80 | MAOA (0.66) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL19938053 | 0.80 | MAOA (0.66) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016077818-A1 | METHOD FOR TREATING, PREVENTING, OR REDUCING THE RISK OF SKIN INFECTION | MELINTA THERAPEUTICS, INC. (US) | 2016-05-19 | — | — | WO | disclosed |