Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880845 | 0.81 | RECQL (0.47) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL13257963 | 0.80 | NPC1 (0.54) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL12319819 | 0.76 | NPC1 (0.47) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL20197190 | 0.76 | NPC1 (0.50) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL18799832 | 0.76 | NPC1 (0.50) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL23450303 | 0.75 | ALDH1A1 (0.41) | HTTMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL18922040 | 0.72 | NPC1 (0.47) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL18922038 | 0.71 | RECQL (0.53) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL13062939 | 0.70 | RECQL (0.49) | HTTMAPTRECQLRAB9ANPC1 | |
| SCHEMBL22646247 | 0.69 | RECQL (0.44) | HTTMAPTRECQLRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160141524-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-05-19 | — | — | US | disclosed |