Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257963 | 0.83 | NPC1 (0.54) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL17762990 | 0.81 | HTT (0.44) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL9315559 | 0.79 | GAA (0.53) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL20197190 | 0.79 | NPC1 (0.50) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL18799832 | 0.79 | NPC1 (0.50) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL3432490 | 0.77 | KDM4E (0.45) | MAPTGAADHODHRAB9ANPC1 | |
| SCHEMBL3432487 | 0.77 | KDM4E (0.45) | MAPTGAADHODHRAB9ANPC1 | |
| SCHEMBL21164058 | 0.76 | RAB9A (0.48) | MAPTHTTRAB9ANPC1HPGD | |
| SCHEMBL12319819 | 0.75 | NPC1 (0.47) | RECQLMAPTHTTGAADHODH | |
| SCHEMBL18922040 | 0.75 | NPC1 (0.47) | RECQLMAPTHTTGAADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423137-B1 | LIPOPEPTIDE STEREOISOMERS, METHODS FOR PREPARING SAME, AND USEFUL INTERMEDIATES | CUBIST PHARM INC (US) | 2009-04-29 | — | — | EP | disclosed |