⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555288 | 0.82 | ADH1B (0.50) | — | |
| SCHEMBL12087846 | 0.82 | — | — | |
| SCHEMBL17763499 | 0.78 | LMNA (0.34) | — | |
| SCHEMBL57190 | 0.78 | CYP2C19 (0.38) | — | |
| SCHEMBL26724193 | 0.77 | — | — | |
| SCHEMBL28488530 | 0.76 | — | — | |
| SCHEMBL1092293 | 0.76 | CYP2C19 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28741000 | 0.76 | CYP2C19 (0.36) | — | |
| SCHEMBL821366 | 0.76 | — | — | |
| SCHEMBL111512 | 0.76 | EPHX1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224265-A1 | HYDROXY SILANE AS AN ADHESION PROMOTER OR CROSS-LINKING AGENT | Sika Technology AG (CH) | 2017-10-04 | — | — | EP | disclosed |
| US-20170240780-A1 | HYDROXY SILANE AS AN ADHESION PROMOTER OR CROSS-LINKING AGENT | SIKA TECHNOLOGY AG (CH) | 2017-08-24 | — | — | US | disclosed |
| WO-2016083311-A1 | HYDROXY SILANE AS AN ADHESION PROMOTER OR CROSS-LINKING AGENT | SIKA TECHNOLOGY AG (CH) | 2016-06-02 | — | — | WO | disclosed |
| EP-3023429-A1 | Hydroxysilane as adhesion promoters or crosslinkers | Sika Technology AG (CH) | 2016-05-25 | — | — | EP | disclosed |