Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968862 | 0.77 | HTT (0.54) | KMT2AHTTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5647289 | 0.76 | HPGD (0.56) | KMT2AHTTGAAALDH1A1MEN1 | |
| SCHEMBL29504659 | 0.76 | HTT (0.56) | KMT2AHTTGAAALDH1A1LMNA | |
| SCHEMBL1173860 | 0.76 | HTT (0.56) | KMT2AHTTGAAALDH1A1LMNA | |
| SCHEMBL30335331 | 0.76 | HTT (0.56) | KMT2AHTTGAAALDH1A1LMNA | |
| SCHEMBL2457558 | 0.76 | HTT (0.52) | KMT2AHTTALDH1A1SMN1; SMN2MKNK1 | |
| SCHEMBL10175121 | 0.75 | SLC6A4 (0.51) | KDM2BKMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL9665275 | 0.74 | SLC18A3 (0.56) | HDAC1KMT2AHTTGAAALDH1A1 | |
| SCHEMBL31227976 | 0.74 | BCAT2 (0.67) | KMT2AHTTMKNK1MKNK2CYP2A6 | |
| SCHEMBL167082 | 0.74 | BCAT2 (0.67) | KMT2AHTTMKNK1MKNK2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751875-B2 | Quinine compounds, and optical isomers, preparation method and medical use thereof | BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2017-09-05 | — | — | US | disclosed |
| US-20160244439-A1 | QUININE COMPOUNDS, AND OPTICAL ISOMERS, PREPARATION METHOD AND MEDICAL USE THEREOF | BEIJING SHOWBY PHARMACEUTICAL CO., LTD. (CN) | 2016-08-25 | — | — | US | disclosed |
| EP-3023424-A1 | QUININE COMPOUNDS, AND OPTICAL ISOMERS, PREPARATION METHOD AND MEDICAL USE THEREOF | Beijing Fswelcome Technology Development Co., Ltd (CN) | 2016-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160244439-A1 | QUININE COMPOUNDS, AND OPTICAL ISOMERS, PREPARATION METHOD AND MEDICAL USE THEREOF | CHRM1, CHRM2, CHRM3 | KDM2B 3958/4885HDAC3 1892/4885HDAC1 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.