Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173860 | 1.00 | HTT (0.56) | HTTKMT2AMKNK1MKNK2DHODH | |
| SCHEMBL29504659 | 1.00 | HTT (0.56) | HTTKMT2AMKNK1MKNK2DHODH | |
| SCHEMBL10968862 | 0.87 | HTT (0.54) | HTTKMT2AMKNK1MKNK2DHODH | |
| Pyridine SCHEMBL9227339 | 0.87 | ALDH1A1 (0.58) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2457558 | 0.85 | HTT (0.52) | HTTKMT2AMKNK1MKNK2DHODH | |
| SCHEMBL10364611 | 0.85 | MKNK1 (0.56) | HTTKMT2AMKNK1MKNK2DHODH | |
| SCHEMBL30705023 | 0.85 | MKNK1 (0.56) | HTTKMT2AMKNK1MKNK2DHODH | |
| Pyrimidine SCHEMBL9228494 | 0.85 | CHRNB2 (0.55) | HTTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28790988 | 0.85 | HNF4A (0.56) | HTTKMT2AMKNK1MKNK2DHODH | |
| SCHEMBL11614420 | 0.85 | NPC1 (0.63) | HTTKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026102082-A1 | ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE | DEEP APPLE THERAPEUTICS, INC. (US) | 2026-05-15 | — | — | WO | disclosed |
| CN-116234549-A | Salt-induced kinase inhibitors | 总医院公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115916748-A | Indole derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-04-04 | — | — | CN | disclosed |