SCHEMBL17764548

SCHEMBL17764548

CCCCOCCOCCO.CCOC(C)OCC

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
MAPT P10636 2/20 0.59
THRB P10828 1/20 0.59
HTT P42858 1/20 0.59
LMNA P02545 2/20 0.46
ALDH1A1 P00352 3/20 0.43
MAPK1 P28482 2/20 0.41
CYP3A4 P08684 2/20 0.41
USP2 O75604 2/20 0.41
CASP1 P29466 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLCO1B3 Q9NPD5 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
GBA2 Q9HCG7 2/20 0.33
HSD17B10 Q99714 1/20 0.33
GBA1 P04062 1/20 0.33
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL10711395 0.88 LMNA (0.60) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL2721224 0.86 TSHR (0.61) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL2721221 0.86 TSHR (0.61) TSHRMEN1KMT2AMAPTTHRB
Di(Hydroxyethyl)Ether SCHEMBL28119437 0.86 TSHR (0.67) TSHRMEN1KMT2AMAPTTHRB
Diethylene Glycol Monoethyl Ether SCHEMBL2952919 0.86 ALDH1A1 (0.61) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL5275388 0.86 LMNA (0.52) TSHRMEN1KMT2AMAPTTHRB
Triethylene Glycol SCHEMBL21903477 0.86 LMNA (0.52) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL23794957 0.83 TSHR (0.94) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL8634565 0.83 TSHR (0.94) TSHRMEN1KMT2AMAPTTHRB
SCHEMBL15619 0.83 TSHR (0.94) TSHRMEN1KMT2AMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9982867-B2 Wavelength converting member and light source device having the wavelength converting member NICHIA CORPORATION (JP) 2018-05-29 US disclosed
US-9972751-B2 Method for manufacturing wavelength conversion member NICHIA CORPORATION (JP) 2018-05-15 US disclosed
US-20160348857-A1 WAVELENGTH CONVERTING MEMBER AND LIGHT SOURCE DEVICE HAVING THE WAVELENGTH CONVERTING MEMBER NICHIA CORPORATION (JP) 2016-12-01 US disclosed
US-20160149097-A1 WAVELENGTH CONVERSION MEMBER, METHOD FOR MANUFACTURING THE SAME, AND LIGHT EMITTING DEVICE NICHIA CORPORATION (JP) 2016-05-26 US disclosed