Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557200 | 0.91 | ALDH1A1 (0.61) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Water SCHEMBL16335551 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL21943784 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL21204252 | 0.73 | ALDH1A1 (0.59) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL20217125 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TSHRGLA | |
| SCHEMBL286789 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL4603063 | 0.72 | ALDH1A1 (0.63) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL26643867 | 0.72 | ALDH1A1 (0.58) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL8171774 | 0.71 | ALDH1A1 (0.52) | ALDH1A1TSHRGLAMEN1KMT2A | |
| Ether SCHEMBL27287732 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689505-B2 | Microspheres | MERCK PATENT GMBH (DE) | 2020-06-23 | — | — | US | disclosed |
| US-20170152372-A1 | MICROSPHERES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20160145421-A1 | MICROSPHERES | MERCK PATENT GMBH (DE) | 2016-05-26 | — | — | US | disclosed |