SCHEMBL4603063

SCHEMBL4603063

CCN(C(C)=S)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
GLA P06280 1/20 0.63
TSHR P16473 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.58
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
PKM P14618 1/20 0.50
HPGD P15428 2/20 0.49
KDM4E B2RXH2 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TP53 P04637 2/20 0.49
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276930 0.91 ALDH1A1 (0.63) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL11423478 0.86 ALDH1A1 (0.63) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL11833504 0.85 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL5458866 0.84 ALDH1A1 (0.61) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL1285989 0.83 ALDH1A1 (0.59) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL8392587 0.83 ALDH1A1 (0.59) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL11757993 0.83 ALDH1A1 (0.59) ALDH1A1GLATSHRL3MBTL1MEN1
SCHEMBL145553 0.83 ALDH1A1 (0.59) ALDH1A1GLATSHRL3MBTL1MEN1
Ammonia Solution, Strong SCHEMBL11521448 0.81 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1MEN1
Zinc Ion SCHEMBL5458862 0.81 ALDH1A1 (0.57) ALDH1A1GLATSHRL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319540-B2 HIF 1-alpha antisense oligonucleotides OLIPASS CORPORATION (KR) 2022-05-03 US disclosed
US-11162104-B2 SCN9A antisense pain killer OLIPASS CORPORATION (KR) 2021-11-02 US disclosed
US-20210292767-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2021-09-23 US disclosed
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-11-14 US disclosed
US-20190218255-A1 SCN9A ANTISENSE OLIGONUCLEOTIDES OLIPASS CORPORATION (KR) 2019-07-18 US disclosed
EP-1694748-B1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES CO (US) 2008-04-23 EP disclosed
US-7273531-B2 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-25 US disclosed
EP-1694748-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M Innovative Properties Company (US) 2006-08-30 EP disclosed
WO-2005047373-A1 METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-26 WO disclosed
US-20050092429-A1 Method of modifying a fluoropolymeric substrate and composite articles thereby 3M INNOVATIVE PROPERTIES COMPANY 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319540-B2 HIF 1-alpha antisense oligonucleotides HIF1A, HIF1AN, UPF1 ALDH1A1 1277/4885GLA 3772/4885TSHR 2223/4885
US-20190345202-A1 ANDROGEN RECEPTOR ANTISENSE OLIGONUCLEOTIDES AR, NR5A1, NR5A2 ALDH1A1 2699/4885GLA 3755/4885TSHR 694/4885
US-20210292767-A1 HIF 1-ALPHA ANTISENSE OLIGONUCLEOTIDES HIF1A, HIF1AN, UPF1 ALDH1A1 1277/4885GLA 3772/4885TSHR 2223/4885
US-20190218255-A1 SCN9A ANTISENSE OLIGONUCLEOTIDES SCN9A, SCN7A, SCN8A ALDH1A1 3949/4885GLA 4409/4885TSHR 2571/4885
US-11162104-B2 SCN9A antisense pain killer SCN9A, SCN7A, SCN8A ALDH1A1 3390/4885GLA 4621/4885TSHR 3763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.