Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1775567 | 0.99 | CYP2C19 (0.43) | CYP2C19USP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1774912 | 0.89 | HTR6 (0.43) | CYP2C19USP2CYP1A2CYP3A4CLK4 | |
| Hydrochloric Acid SCHEMBL1774669 | 0.88 | HTR6 (0.42) | CYP2C19USP2CYP1A2CYP3A4CLK4 | |
| SCHEMBL1775158 | 0.85 | HTR2C (0.44) | HTR6HTR2CDRD2 | |
| SCHEMBL1776434 | 0.85 | HTR2C (0.44) | HTR6HTR2CNCF1DRD2 | |
| Hydrochloric Acid SCHEMBL1775915 | 0.84 | HTR6 (0.43) | HTR6HTR2CDRD2MAPT | |
| Hydrochloric Acid SCHEMBL1776291 | 0.84 | HTR6 (0.43) | HTR6HTR2CNCF1DRD2MAPT | |
| SCHEMBL1774794 | 0.84 | HTR2C (0.55) | HTR6HTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL1774267 | 0.83 | HTR2C (0.54) | HTR6HTR2CDRD2 | |
| SCHEMBL1775605 | 0.82 | HTR6 (0.56) | HTR6HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943639-B2 | Such as 6-benzenesulfonyl-4-piperazin-1-yl-quinoline hydrochloride; for treatment of central nervous system and/or 5- HT6 receptor related disorders; for weight gain/loss | PROXIMAGEN LIMITED (GB) | 2011-05-17 | — | — | US | claimed |