SCHEMBL1777073

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1779469	0.89	GSK3A (0.69)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1778473	0.86	GSK3A (0.54)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1777268	0.86	GSK3A (0.69)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1778251	0.86	GSK3A (0.57)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1777538	0.83	GSK3A (0.53)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL6852671	0.83	GSK3A (0.58)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1777932	0.82	GSK3A (0.49)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL1777077	0.81	GSK3A (0.47)	GSK3AGSK3BCDK1CCNB2CCNB1
	SCHEMBL24099177	0.77	APOL1 (0.63)	SRCAPOL1
	SCHEMBL22747691	0.76	EGFR (0.65)	SRCAPOL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.