Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demannose SCHEMBL1334995 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Galactose SCHEMBL423422 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL29844979 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Galactose SCHEMBL31555927 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL3630269 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL21456966 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Galactose SCHEMBL30458008 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL29395609 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL13277644 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 | |
| Demannose SCHEMBL8560244 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637722-A1 | 25-HYDROXY-CHOLEST-5-EN-3-SULFATE CHOLINE, FORMULATIONS THEREOF AND METHODS FOR PREPARING, AND MEDICAL USES OF SAME | Durect Corporation (US) | 2025-10-29 | — | — | EP | claimed |
| EP-4630505-A2 | PEROVSKITE PHOTOVOLTAIC DEVICE AND SOLUTION-PROCESSED METHOD FOR MANUFACTURE | Swansea University (GB) | 2025-10-15 | — | — | EP | claimed |
| US-20250302033-A1 | SOLUTIONS AND METHODS FOR FORMING AN EXOGENOUS FLEXIBLE FILM ON A PLANT AND PLANTS INCLUDING THE EXOGENOUS FLEXIBLE FILM | Cultiva, LLC | 2025-10-02 | — | — | US | claimed |
| EP-4615421-A1 | GALANTAMINE MINITABLETS | Rejuvenate Biomed NV (BE) | 2025-09-17 | — | — | EP | claimed |
| WO-2024177520-A9 | PHARMACEUTICAL COMPOSITION COMPRISING FLURALANER, MOXIDECTIN AND PRAZIQUANTEL FOR TREATING PARASITIC INFESTATIONS IN SMALL ANIMALS | AGROVET MARKET S.A. (PE) | 2025-07-17 | — | — | WO | claimed |
| US-12349674-B2 | Solutions and methods for forming an exogenous flexible film on a plant and plants including the exogenous flexible film | Cultiva, LLC (US) | 2025-07-08 | — | — | US | claimed |
| CN-120137570-A | Multiband absorption optical cement applied to full lamination and preparation method thereof | 江苏华玻光电技术有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120058295-A | Environment-friendly ready-mixed mortar for wall and preparation method thereof | 徐州市江山新型建材有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120036084-A | Construction method of coal mining subsidence land sponge field | 江苏浩坤地理信息科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119977450-A | Adhesive for large brick and ceramic tile and manufacturing method thereof | 堡密特建筑材料(苏州)有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-114369749-A | Alloy screw material and production process of screw thereof | 上海友川技术有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-113213833-B | Fly ash-based foam geopolymer and preparation method and application thereof | 深圳大学 | 2022-04-19 | — | — | CN | claimed |
| CN-112159574-B | Titanate chelating agent, environment-friendly boron-free high-molecular polyvinyl alcohol-based ultralight clay and preparation method thereof | 漯河市罗弗文具制造有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-114335557-A | Composite foil, preparation method, current collector and lithium ion battery | 蜂巢能源科技有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-111872316-B | 3D printing sand additive and application thereof | 天津致勤新型材料有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-111099871-B | Gypsum-based self-leveling material and application method thereof in artware | 同济大学 | 2022-04-05 | — | — | CN | claimed |
| CN-110194641-B | Interface-enhanced phosphogypsum light inner wall partition board and preparation method thereof | 武汉理工大学 | 2022-04-01 | — | — | CN | claimed |
| CN-111333789-B | Preparation method of microcapsule type polycarboxylate superplasticizer with high-temperature long-term slump retaining performance | 江苏苏博特新材料股份有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-113998928-A | Environment-friendly micro-expansion waterproof building glue and use method thereof | 鞍钢建设集团有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-107778378-A | Mannose-modified chitosan stearic acid grafting and preparation and application | 浙江大学 | 2018-03-09 | — | — | CN | claimed |