Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743254 | 0.86 | SLC9A1 (0.46) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL10491406 | 0.86 | SLC9A1 (0.44) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL11395709 | 0.86 | SLC9A1 (0.44) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL10743257 | 0.86 | SLC9A1 (0.46) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL10743245 | 0.86 | SLC9A1 (0.46) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL11395714 | 0.85 | SLC9A1 (0.45) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL10491421 | 0.85 | SLC9A1 (0.45) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL15977340 | 0.84 | SLC9A1 (0.44) | SLC9A1GAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL20076696 | 0.82 | GAA (0.44) | SLC9A1KMT2AGAAMAPTMAPK1 | |
| SCHEMBL18927360 | 0.82 | SLC9A1 (0.62) | SLC9A1KMT2AMAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2670731-B1 | POSITIVE ALLOSTERIC MODULATORS OF THE ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR AND USES THEREOF. | BIONOMICS LTD (AU) | 2016-05-25 | — | — | EP | disclosed |