⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227417 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL3434601 | 0.69 | — | — | |
| SCHEMBL10919262 | 0.69 | — | — | |
| SCHEMBL28303423 | 0.67 | — | — | |
| SCHEMBL15338442 | 0.67 | — | — | |
| SCHEMBL31440713 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL14318880 | 0.67 | — | — | |
| SCHEMBL8083331 | 0.67 | — | — | |
| SCHEMBL1419351 | 0.65 | — | — | |
| SCHEMBL28489036 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216607-A1 | LABELING OF A PROTEIN OR A POLYPEPTIDE | ETH ZURICH (CH) | 2020-10-29 | — | — | WO | disclosed |
| EP-1868998-B1 | NEW HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTI-ALZHEIMER AGENTS | VFP THERAPIES (FR) | 2016-05-25 | — | — | EP | disclosed |