Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329562 | 0.88 | TOP2A (0.55) | TOP2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL22015414 | 0.86 | TOP2A (0.44) | TOP2AALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL21894264 | 0.85 | TOP2A (0.42) | TOP2AALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL8775559 | 0.84 | TOP2A (0.35) | TOP2ANOTUM | |
| SCHEMBL12737551 | 0.81 | TOP2A (0.40) | TOP2AALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL5570112 | 0.80 | PDE4A (0.35) | TOP2AFFAR4NOTUM | |
| SCHEMBL22015244 | 0.70 | MAPT (0.35) | TOP2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL19073274 | 0.70 | TOP2A (0.38) | TOP2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL13944015 | 0.70 | TOP2A (0.38) | TOP2AALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL12737553 | 0.69 | TOP2A (0.47) | TOP2AALDH1A1KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079757-A2 | NOVEL PROCESSES FOR PREPARING 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | SYMED LABS LIMITED (IN) | 2016-05-26 | — | — | WO | disclosed |