Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | BMX | P51813 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17777421 | 0.92 | KDM4E (0.49) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL30007178 | 0.92 | KDM4E (0.49) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL25585066 | 0.91 | MAPK14 (0.38) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL17777577 | 0.91 | KDM4E (0.43) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL17714853 | 0.90 | KDM4E (0.50) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL30466673 | 0.90 | KDM4E (0.50) | KDM4EATML3MBTL1CYP1A2MAPK14 | |
| SCHEMBL17777423 | 0.90 | ATM (0.44) | KDM4EATML3MBTL1MAPK14MEN1 | |
| SCHEMBL19997897 | 0.90 | MAPK14 (0.39) | KDM4EATML3MBTL1MAPK14PTGDR2 | |
| SCHEMBL30257606 | 0.90 | CYP1A2 (0.40) | KDM4ECYP1A2MAPK14PTGDR2CNR1 | |
| SCHEMBL26191632 | 0.90 | L3MBTL1 (0.40) | KDM4EATML3MBTL1CYP1A2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10957859-B2 | Heterocyclic compounds for use in electronic devices | MERCK PATENT GMBH (DE) | 2021-03-23 | — | — | US | disclosed |
| US-20170324038-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| US-20170324038-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-09 | — | — | US | disclosed |
| WO-2016078747-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170324038-A1 | HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES | DDT, VDAC2, VDAC3 | KDM4E 2237/4885ATM 4659/4885L3MBTL1 2548/4885 |
| US-10957859-B2 | Heterocyclic compounds for use in electronic devices | DDT, VDAC2, VDAC3 | KDM4E 2237/4885ATM 4659/4885L3MBTL1 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.