⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959924 | 0.77 | — | — | |
| SCHEMBL2900989 | 0.77 | — | — | |
| SCHEMBL167589 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL10741447 | 0.76 | — | — | |
| SCHEMBL5489826 | 0.74 | TAAR1 (0.40) | — | |
| SCHEMBL906626 | 0.73 | — | — | |
| SCHEMBL15761494 | 0.72 | HTR1D (0.42) | — | |
| SCHEMBL10378155 | 0.72 | TAAR1 (0.61) | — | |
| SCHEMBL1362592 | 0.72 | NISCH (0.65) | — | |
| Ethylenediamine SCHEMBL14335529 | 0.71 | ADRA2B (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943612-B2 | Compounds that modulate PPAR activity, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090048257-A1 | COMPOUNDS THAT MODULATE PPAR ACTIVITY, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS, LLC | 2009-02-19 | — | — | US | disclosed |