Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550680 | 0.87 | TRPV1 (0.40) | CTSSAXLHTT | |
| SCHEMBL17778342 | 0.83 | L3MBTL1 (0.40) | HTTL3MBTL1EPHX2 | |
| SCHEMBL17769634 | 0.82 | TRPV1 (0.39) | CTSSHTT | |
| SCHEMBL17778339 | 0.82 | MEN1 (0.38) | L3MBTL1EPHX2HTR1AADRA1A | |
| SCHEMBL20550415 | 0.78 | JAK2 (0.35) | CTSS | |
| SCHEMBL16754541 | 0.77 | TRPV1 (0.40) | CTSSAXLHTT | |
| SCHEMBL17770366 | 0.77 | TRPV1 (0.40) | CTSSAXLHTT | |
| SCHEMBL20550312 | 0.77 | TRPV1 (0.35) | CTSS | |
| SCHEMBL20550605 | 0.75 | GSK3B (0.43) | — | |
| SCHEMBL19713784 | 0.73 | TRPV1 (0.39) | CTSSHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079712-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |