Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778342 | 0.88 | L3MBTL1 (0.40) | MEN1KMT2AEPHX2DRD2L3MBTL1 | |
| SCHEMBL17769452 | 0.86 | MEN1 (0.39) | MEN1KMT2AOPRK1 | |
| SCHEMBL17778483 | 0.82 | OPRK1 (0.40) | OPRK1 | |
| SCHEMBL17778340 | 0.82 | CTSS (0.37) | EPHX2L3MBTL1ADRA1AHTR1A | |
| SCHEMBL17769757 | 0.75 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL17769352 | 0.75 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL17769420 | 0.75 | IRAK4 (0.39) | L3MBTL1OPRK1 | |
| SCHEMBL17769756 | 0.74 | TRPV1 (0.39) | MEN1KMT2ADRD2L3MBTL1 | |
| SCHEMBL17777041 | 0.74 | MEN1 (0.39) | MEN1KMT2A | |
| SCHEMBL17778411 | 0.71 | SORD (0.34) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079712-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |