Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.44 |
| ▸ | HTR2C | P28335 | 12/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17778683 | 1.00 | HTR2A (0.44) | HTR2AHTR2CMEN1LMNATP53 | |
| SCHEMBL17767906 | 1.00 | HTR2A (0.44) | HTR2AHTR2CMEN1LMNATP53 | |
| SCHEMBL17768200 | 0.85 | HTR2C (0.48) | HTR2AHTR2CTRPV1 | |
| SCHEMBL17778725 | 0.85 | HTR2C (0.48) | HTR2AHTR2CTRPV1 | |
| SCHEMBL16249988 | 0.85 | HTR2C (0.48) | HTR2AHTR2CTRPV1 | |
| SCHEMBL17767930 | 0.85 | HTR2A (0.39) | HTR2AHTR2CMEN1TP53KMT2A | |
| SCHEMBL19689818 | 0.84 | HTR2A (0.40) | HTR2AHTR2CMEN1TP53KMT2A | |
| SCHEMBL17778706 | 0.84 | HTR2A (0.40) | HTR2AHTR2CMEN1TP53KMT2A | |
| SCHEMBL17778719 | 0.82 | MALT1 (0.41) | MEN1KMT2ATRPV1 | |
| SCHEMBL17767954 | 0.82 | MALT1 (0.41) | MEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |