Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.31 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.31 |
| ▸ | MYLK2 | Q9H1R3 | 2/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.31 |
| ▸ | BMP2K | Q9NSY1 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19689719 | 1.00 | CSF1R (0.35) | CSF1RABL1WNT3ATLR9TLR8 | |
| SCHEMBL19689720 | 1.00 | CSF1R (0.35) | CSF1RABL1WNT3ATLR9TLR8 | |
| SCHEMBL17768146 | 0.90 | RAF1 (0.34) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL17768148 | 0.90 | RAF1 (0.34) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL19706670 | 0.90 | RAF1 (0.34) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL19706747 | 0.90 | WNT3A (0.33) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL17768229 | 0.90 | WNT3A (0.33) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL17768231 | 0.90 | WNT3A (0.33) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL17618758 | 0.89 | WNT3A (0.35) | ABL1WNT3ATLR9TLR8TLR7 | |
| SCHEMBL19689755 | 0.89 | KIF18A (0.34) | WNT3ATLR9TLR8TLR7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079709-A1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-05-26 | — | — | WO | disclosed |