Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.71 |
| ▸ | MAPT | P10636 | 10/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410895 | 0.85 | KDM4E (0.85) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17779067 | 0.80 | KDM4E (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16410901 | 0.78 | RAB9A (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL13833701 | 0.76 | KDM4E (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17774410 | 0.72 | KDM4E (0.70) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16410891 | 0.71 | MAPT (0.53) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL17774412 | 0.70 | MEN1 (0.62) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16410900 | 0.69 | POLB (0.65) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16410902 | 0.67 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL694406 | 0.67 | NPSR1 (0.66) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145250-A1 | ANTI-CANCER COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145250-A1 | ANTI-CANCER COMPOUNDS | SKP2, TP53, TEAD2 | ALDH1A1 353/4885KDM4E 472/4885MAPT 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.