SCHEMBL17779146

SCHEMBL17779146

COc1ccc(N2c3ccc(C=C4C(=O)c5cc6ccccc6cc5C4=O)cc3C(C)(C)c3ccc4ccccc4c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
PGR P06401 1/20 0.39
KDM1A O60341 2/20 0.38
LCK P06239 1/20 0.38
USP2 O75604 1/20 0.38
PKM P14618 1/20 0.38
HSD11B1 P28845 1/20 0.36
ABCB1 P08183 1/20 0.36
GAPDH P04406 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALPL P05186 1/20 0.35
ALPI P09923 1/20 0.35
ALPG P10696 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ERO1A Q96HE7 1/20 0.35
PSMB5 P28074 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17773933 0.91 ERO1A (0.38) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL17779147 0.88 KMT2A (0.45) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL17778892 0.88 KMT2A (0.45) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL15118395 0.82 MAPT (0.36) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL15118397 0.82 MAPT (0.35) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL17779112 0.81 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL17778894 0.81 KMT2A (0.41) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL15118363 0.80 ALDH1A1 (0.33) MAPTALDH1A1KDM4E
SCHEMBL15118356 0.79 ALDH1A1 (0.36) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL17773868 0.79 LCK (0.39) KMT2AMAPTMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997721-B2 Photoelectric conversion material, photoelectric conversion element, optical sensor, and imaging element FUJIFILM CORPORATION (JP) 2018-06-12 US disclosed
US-20160149144-A1 PHOTOELECTRIC CONVERSION MATERIAL, PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL SENSOR, AND IMAGING ELEMENT FUJIFILM CORPORATION (JP) 2016-05-26 US disclosed