Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156127 | 0.96 | ALOX5 (0.41) | SIRT2SIRT1MAPTKDM4EMEN1 | |
| SCHEMBL17760251 | 0.92 | SIRT2 (0.39) | SIRT2SIRT1MAPTKDM4EMEN1 | |
| SCHEMBL25124648 | 0.91 | SIRT2 (0.39) | SIRT2SIRT1MAPTKDM4EMEN1 | |
| SCHEMBL18294162 | 0.91 | PIM3 (0.40) | MAPTKDM4EMEN1GLAGAA | |
| SCHEMBL29514897 | 0.89 | PTGIR (0.48) | MAPTKDM4EMEN1GLAGAA | |
| SCHEMBL18216689 | 0.89 | PTGIR (0.48) | MAPTKDM4EMEN1GLAGAA | |
| SCHEMBL23168466 | 0.89 | MAPT (0.43) | MAPTKDM4EMEN1GLAGAA | |
| SCHEMBL17760764 | 0.89 | ALK (0.38) | SIRT2SIRT1MAPTKDM4EMEN1 | |
| SCHEMBL25536385 | 0.89 | FADS1 (0.41) | SIRT2SIRT1MAPTKDM4EMEN1 | |
| SCHEMBL17968618 | 0.88 | FABP3 (0.43) | MAPTMEN1KMT2ATDP1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016079667-A1 | INDOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-26 | — | — | WO | disclosed |