Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10940755 | 0.96 | CYP2C19 (0.39) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4429302 | 0.89 | PARP1 (0.36) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28043401 | 0.84 | CYP3A4 (0.36) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14880000 | 0.83 | CYP2C19 (0.39) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6907567 | 0.83 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL8567197 | 0.83 | CYP2C19 (0.33) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11106658 | 0.82 | CYP3A4 (0.36) | CYP2C19CYP3A4SMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL4811574 | 0.82 | CYP2C19 (0.41) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL17775400 | 0.82 | PTPN1 (0.31) | ALDH1A1 | |
| SCHEMBL14635820 | 0.81 | CYP2C19 (0.40) | CYP2C19CYP3A4POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160145273-A1 | PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2016-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145273-A1 | PRECATALYST FOR SHIBASAKI'S RARE EARTH METAL BINOLATE CATALYSTS | TBCB, RUVBL2, RHEB | CYP2C19 3621/4885CYP3A4 2586/4885POLB 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.