Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.35 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 2/20 | 0.35 |
| ▸ | CCND1 | P24385 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17682947 | 0.86 | MCL1 (0.45) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL17683003 | 0.85 | MCL1 (0.45) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL17682969 | 0.85 | MCL1 (0.45) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL27333122 | 0.83 | HSD17B1 (0.47) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL17682950 | 0.83 | ESR2 (0.46) | PDCD1CD274HSD17B1HSD17B2ESR2 | |
| SCHEMBL27749171 | 0.82 | HPGD (0.64) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL17683013 | 0.81 | ESR2 (0.43) | HSD17B1HSD17B2ESR2ESR1ALOX5 | |
| SCHEMBL17682964 | 0.77 | MCL1 (0.43) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 | |
| SCHEMBL17779750 | 0.77 | HSD17B1 (0.43) | ALDH1A1HPGDBCL2L1HSD17B10HSD17B1 | |
| SCHEMBL17470594 | 0.76 | CD274 (0.44) | ALDH1A1HPGDBCL2L1HSD17B10PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160149139-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-05-26 | — | — | US | disclosed |