Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17683013 | 0.97 | ESR2 (0.43) | ESR2HSD17B1HSD17B2HDAC4HDAC2 | |
| SCHEMBL17682947 | 0.88 | MCL1 (0.45) | ESR2HSD17B1HSD17B2ALOX5ESR1 | |
| SCHEMBL17779814 | 0.87 | HSD17B1 (0.47) | ESR2HSD17B1HSD17B2HDAC4HDAC2 | |
| SCHEMBL17682969 | 0.87 | MCL1 (0.45) | ESR2HSD17B1HSD17B2HDAC8ALOX5 | |
| SCHEMBL17683003 | 0.87 | MCL1 (0.45) | ESR2HSD17B1HSD17B2HDAC8ALOX5 | |
| SCHEMBL17682966 | 0.85 | HSD17B1 (0.45) | ESR2HSD17B1HSD17B2HDAC4HDAC2 | |
| SCHEMBL17779761 | 0.83 | ALDH1A1 (0.43) | ESR2HSD17B1HSD17B2ALOX5ESR1 | |
| SCHEMBL17779749 | 0.82 | HSD17B1 (0.47) | ESR2HSD17B1HSD17B2HDAC4HDAC2 | |
| SCHEMBL17682962 | 0.82 | HSD17B1 (0.47) | ESR2HSD17B1HSD17B2HDAC4HDAC2 | |
| SCHEMBL17399879 | 0.81 | ALOX5 (0.40) | ESR2HSD17B1HSD17B2ALOX5ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160149139-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-05-26 | — | — | US | disclosed |
| US-20160104847-A1 | NOVEL COMPOUNDS AND USES IN DEVICES | UNIVERSAL DISPLAY CORPORATION | 2016-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160104847-A1 | NOVEL COMPOUNDS AND USES IN DEVICES | TERT, UACA, TXN | ESR2 2568/4885HSD17B1 4833/4885HSD17B2 4781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.