SCHEMBL17780754

SCHEMBL17780754

CC1(C)OB(c2ccc3c(c2)C2(c4ccccc4-3)c3ccccc3-c3ccc(N(c4ccccc4)c4ccc(-c5ccccc5)cc4)cc32)OC1(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.50
LPL P06858 9/20 0.50
PDK2 Q15119 3/20 0.33
DGAT1 O75907 1/20 0.32
PDGFRB P09619 1/20 0.31
KDR P35968 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
P4HB P07237 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31386271 0.95 LIPG (0.56) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL17986634 0.95 LIPG (0.56) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL18458011 0.92 LIPG (0.46) LIPGLPLPDK2P4HB
SCHEMBL15845388 0.90 LIPG (0.52) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL15906974 0.90 LIPG (0.51) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL24531298 0.90 LIPG (0.54) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL15906991 0.90 LIPG (0.54) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL15907004 0.89 LIPG (0.55) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL16383541 0.88 LIPG (0.50) LIPGLPLPDK2DGAT1PDGFRB
SCHEMBL30951702 0.87 LIPG (0.59) LIPGLPLPDK2DGAT1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10510960-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-12-17 US disclosed
US-20170338414-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-23 US disclosed
US-20170338414-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-11-23 US disclosed
WO-2016078738-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170338414-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885PDK2 1024/4885
US-10510960-B2 Materials for organic electroluminescent devices L1CAM, EFNA1, EPCAM LIPG 2479/4885LPL 4031/4885PDK2 1024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.