Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29224606 | 0.98 | AR (0.47) | ARTRPV4KIF11TAS2R14CYP11B1 | |
| SCHEMBL30945835 | 0.98 | AR (0.47) | ARTRPV4KIF11TAS2R14CYP11B1 | |
| SCHEMBL3480548 | 0.85 | KIF11 (0.56) | ARKIF11CYP11B1CYP11B2 | |
| SCHEMBL29546917 | 0.83 | AR (0.52) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL12151755 | 0.83 | AR (0.52) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL495426 | 0.79 | CYP11B1 (0.57) | ARTRPV4KIF11TAS2R14CYP11B1 | |
| SCHEMBL1996075 | 0.79 | AR (0.73) | AR | |
| SCHEMBL964361 | 0.79 | AR (0.49) | ARKIF11TAS2R14 | |
| SCHEMBL16952881 | 0.78 | AR (0.47) | ARKIF11TAS2R14CYP11B1CYP11B2 | |
| SCHEMBL669827 | 0.78 | AR (0.47) | ARKIF11TAS2R14CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146127-A | Preparation method of 2-methylthio-4-trifluoromethyl benzonitrile | 北京颖泰嘉和生物科技股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2022015624-A1 | SUBSTITUTED DIHYDROPYRAZINEDIONES AS MODULATORS OF THE NMDA RECEPTOR | SCHRÖDINGER, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| CN-109111405-B | Aromatic thioether compound and pesticide and medical application thereof | 南开大学 | 2021-07-30 | — | — | CN | disclosed |
| US-9662328-B2 | Targeting human thymidylate kinase induces DNA repair toxicity in malignant tumor cells | NATIONAL TAIWAN UNIVERSITY (TW) | 2017-05-30 | — | — | US | disclosed |
| CN-106565621-A | Isoxaflutole synthesizing method | 上虞颖泰精细化工有限公司 | 2017-04-19 | — | — | CN | disclosed |
| US-20160151362-A1 | TARGETING HUMAN THYMIDYLATE KINASE INDUCES DNA REPAIR TOXICITY IN MALIGNANT TUMOR CELLS | NATIONAL TAIWAN UNIVERSITY (TW) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160151362-A1 | TARGETING HUMAN THYMIDYLATE KINASE INDUCES DNA REPAIR TOXICITY IN MALIGNANT TUMOR CELLS | DTYMK, TYMP, TK1 | AR 4387/4885TRPV4 4115/4885KIF11 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.