Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177694 | 0.89 | KDM4E (0.50) | NPC1KDM4ETGFBR1CYP2A6NPY5R | |
| SCHEMBL10871976 | 0.85 | ADORA2A (0.41) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL6381236 | 0.85 | TGFBR1 (0.42) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL28423884 | 0.84 | ADORA2A (0.40) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL28365752 | 0.83 | LOXL2 (0.48) | — | |
| SCHEMBL4513178 | 0.82 | CYP2A6 (0.39) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL6384277 | 0.82 | TGFBR1 (0.39) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL923479 | 0.79 | PTGS1 (0.47) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 | |
| SCHEMBL2966928 | 0.79 | KDM4E (0.53) | NPC1KDM4ETGFBR1CYP2A6GAA | |
| SCHEMBL57318 | 0.79 | KDM4E (0.50) | NPC1KDM4ETGFBR1TGFBR2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961259-B2 | Multistimuli-responsive white luminescent materials including metal elements | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-30 | — | — | US | disclosed |
| WO-2016090062-A1 | MULTISTIMULI-RESPONSIVE WHITE LUMINESCENT MATERIALS INCLUDING METAL ELEMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-09 | — | — | WO | disclosed |
| US-20160152638-A1 | MULTISTIMULI-RESPONSIVE WHITE LUMINESCENT MATERIALS INCLUDING METAL ELEMENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-02 | — | — | US | disclosed |