Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19822077 | 1.00 | TLR8 (0.45) | TLR8SMPD1CHRM1CHRM2ADRA2A | |
| SCHEMBL15052591 | 1.00 | TLR8 (0.45) | TLR8SMPD1CHRM1CHRM2ADRA2A | |
| SCHEMBL17791368 | 0.90 | ESR1 (0.42) | TLR8CHRM1CHRM2ADRA2AHTR2B | |
| SCHEMBL19799300 | 0.90 | ESR1 (0.42) | TLR8CHRM1CHRM2ADRA2AHTR2B | |
| SCHEMBL17273703 | 0.89 | TLR8 (0.40) | TLR8CHRM1CHRM2ADRA2AHTR2B | |
| SCHEMBL15826204 | 0.89 | TLR8 (0.40) | TLR8CHRM1CHRM2ADRA2AHTR2B | |
| SCHEMBL6933511 | 0.79 | TLR8 (0.50) | TLR8SMPD1CHRM2ADRA2AHTR2B | |
| SCHEMBL2246934 | 0.79 | TLR8 (0.50) | TLR8SMPD1CHRM2ADRA2AHTR2B | |
| SCHEMBL15172894 | 0.77 | ALDH1A1 (0.55) | TLR8CHRM2ADRA2AHTR2BSLC6A3 | |
| SCHEMBL202536 | 0.76 | NR5A1 (0.45) | TLR8SMPD1CHRM2ADRA2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005956-B2 | Compositions, articles, and methods for down-converting light and other applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-06-26 | — | — | US | disclosed |
| US-20160152890-A1 | COMPOSITIONS, ARTICLES, AND METHODS FOR DOWN-CONVERTING LIGHT AND OTHER APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-02 | — | — | US | disclosed |
| WO-2016086123-A1 | COMPOSITIONS, ARTICLES, AND METHODS FOR DOWN-CONVERTING LIGHT AND OTHER APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-02 | — | — | WO | disclosed |