Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246934 | 1.00 | TLR8 (0.50) | TLR8MCHR1SMPD1ESR1PDE5A | |
| SCHEMBL2367661 | 0.84 | TLR8 (0.54) | TLR8MCHR1LMNAMEN1NR1I2 | |
| SCHEMBL2368074 | 0.84 | TLR8 (0.61) | TLR8MCHR1PDE5APDE4APDE4B | |
| SCHEMBL12510798 | 0.84 | TLR8 (0.61) | TLR8MCHR1PDE5APDE4APDE4B | |
| SCHEMBL28275020 | 0.81 | TLR8 (0.44) | TLR8MCHR1SMPD1ESR1 | |
| SCHEMBL20678487 | 0.79 | TLR8 (0.51) | TLR8MCHR1SMPD1ESR1LMNA | |
| SCHEMBL19822077 | 0.79 | TLR8 (0.45) | TLR8MCHR1SMPD1PDE4ALMNA | |
| SCHEMBL15052591 | 0.79 | TLR8 (0.45) | TLR8MCHR1SMPD1PDE4ALMNA | |
| SCHEMBL17784242 | 0.79 | TLR8 (0.45) | TLR8MCHR1SMPD1PDE4ALMNA | |
| SCHEMBL6743869 | 0.77 | NR5A1 (0.45) | TLR8SMPD1ESR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1365002-A1 | Liquid crystalline derivatives for electronic devices | UNIVERSITE LIBRE DE BRUXELLES (BE) | 2003-11-26 | — | — | EP | disclosed |