Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.69 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.69 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786469 | 0.89 | CSNK2A2 (0.60) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL926774 | 0.87 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL17786530 | 0.85 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| 6,3'-Dimethoxyflavone SCHEMBL516389 | 0.83 | KDM4E (0.82) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| 6,3'-Dimethoxyflavone SCHEMBL30894690 | 0.83 | KDM4E (0.82) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL31675975 | 0.81 | MAPT (1.00) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL4649870 | 0.81 | MAPT (1.00) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL10632007 | 0.81 | KDM4E (0.72) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL17786425 | 0.81 | KDM4E (0.60) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 | |
| SCHEMBL17786357 | 0.81 | MAPT (0.69) | CSNK2A2CSNK2BCSNK2A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083490-A1 | COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES | REMYND NV (BE) | 2016-06-02 | — | — | WO | disclosed |