Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.82 |
| ▸ | HPGD | P15428 | 4/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.82 |
| ▸ | RECQL | P46063 | 2/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 6/20 | 0.81 |
| ▸ | TP53 | P04637 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | TSHR | P16473 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6,3'-Dimethoxyflavone SCHEMBL30894690 | 1.00 | KDM4E (0.82) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31238494 | 0.92 | ABCB1 (0.79) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL312059 | 0.90 | ABCB1 (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL28930176 | 0.90 | ABCB1 (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| 6-Methoxyflavone SCHEMBL30799564 | 0.90 | ABCB1 (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| 7,3'-Dimethoxyflavone SCHEMBL718068 | 0.90 | KDM4E (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31675975 | 0.89 | MAPT (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7079959 | 0.89 | KDM4E (0.73) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4649870 | 0.89 | MAPT (1.00) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL360247 | 0.89 | CYP3A4 (0.82) | KDM4ECYP3A4ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024193071-A1 | NEOTAME OFF-FLAVOR IMPROVER, ATOMIZED ESSENCE, AND AEROSOL GENERATING APPARATUS | 深圳昱朋科技有限公司 | 2024-09-26 | — | — | WO | claimed |
| CN-118102892-A | Composition comprising a nutrient and a taste modifier | 弗门尼舍有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-116268354-B | Neotame peculiar smell modifier, atomized essence and aerosol generating device | 深圳昱朋科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-116268354-A | Neotame peculiar smell modifier, atomized essence and aerosol generating device | 深圳昱朋科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-20130245070-A1 | COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME | THE RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2013-09-19 | — | — | US | claimed |
| US-20110286927-A1 | ATF4 Inhibitors and Their Use for Neural Protection, Repair, Regeneration, and Plasticity | CORNELL UNIVERSITY (US) | 2011-11-24 | — | — | US | claimed |
| US-20090253782-A1 | Compounds for Enhancing Arginase Activity and Methods of USe Thereof | CORNELL RESEARCH FOUNDATION, INC. | 2009-10-08 | — | — | US | claimed |
| WO-2009020601-A2 | ATF4 INHIBITORS AND THEIR USE FOR NEURAL PROTECTION, REPAIR, REGENERATION, AND PLASTICITY | CORNELL UNIVERSITY (US) | 2009-02-12 | — | — | WO | claimed |
| WO-2008011083-A2 | COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USE THEREOF | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-01-24 | — | — | WO | claimed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-20260022384-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2026-01-22 | — | — | US | disclosed |
| WO-2024193071-A1 | NEOTAME OFF-FLAVOR IMPROVER, ATOMIZED ESSENCE, AND AEROSOL GENERATING APPARATUS | 深圳昱朋科技有限公司 | 2024-09-26 | — | — | WO | disclosed |
| CN-118102892-A | Composition comprising a nutrient and a taste modifier | 弗门尼舍有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245070-A1 | COMPOUNDS FOR ENHANCING ARGINASE ACTIVITY AND METHODS OF USING SAME | ARG2, ARG1, OTC | KDM4E 1426/4885CYP3A4 3922/4885ALDH1A1 249/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | KDM4E 2309/4885CYP3A4 3010/4885ALDH1A1 2440/4885 |
| US-20090253782-A1 | Compounds for Enhancing Arginase Activity and Methods of USe Thereof | ARG2, ARG1, OTC | KDM4E 1521/4885CYP3A4 3582/4885ALDH1A1 292/4885 |
| US-20260022384-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | ASNS, AARS1, NARS1 | KDM4E 3487/4885CYP3A4 4666/4885ALDH1A1 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.