Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282566 | 0.85 | KMT2A (0.72) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL7967816 | 0.84 | DHFR (0.49) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL27633513 | 0.83 | KMT2A (0.68) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL259477 | 0.83 | KMT2A (0.68) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL9178009 | 0.82 | KMT2A (1.00) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL9131594 | 0.81 | TNKS2 (0.62) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL8557293 | 0.81 | MAPT (0.97) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL405533 | 0.81 | PDE5A (0.65) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL9129643 | 0.78 | KDM4C (0.56) | KMT2AMAPTGAAPKMKDM4E | |
| SCHEMBL3762307 | 0.78 | MAPT (0.76) | KMT2AMAPTGAAPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016083490-A1 | COMPOUNDS FOR THE TREATMENT OF AMYLOID-ASSOCIATED DISEASES | REMYND NV (BE) | 2016-06-02 | — | — | WO | disclosed |