Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7352414 | 0.86 | LMNA (0.44) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL12075533 | 0.81 | CCR1 (0.53) | LMNACYP3A4KDM4EMAPTMTOR | |
| 2-Phenylimidazole SCHEMBL27944740 | 0.79 | LMNA (0.62) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL14900763 | 0.77 | LMNA (0.59) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL12470533 | 0.77 | LMNA (0.64) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL28462536 | 0.77 | LMNA (0.54) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL27681790 | 0.76 | LMNA (0.73) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL669488 | 0.75 | LMNA (0.61) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL4246178 | 0.75 | LMNA (0.61) | LMNACYP3A4KDM4EMAPTMTOR | |
| SCHEMBL28724677 | 0.75 | LMNA (0.70) | LMNACYP3A4KDM4EMAPTMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102491987-B | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2014-06-11 | — | — | CN | claimed |
| CN-102491987-A | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2012-06-13 | — | — | CN | claimed |
| WO-2016086022-A2 | HETEROAROMATIC IMIDAZOLYL COMPOUNDS AND METHODS FOR TREATING CANCER | CHANNEL THERAPEUTICS, INC. (US) | 2016-06-02 | — | — | WO | disclosed |
| CN-102491987-B | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2014-06-11 | — | — | CN | disclosed |
| CN-102491987-A | 1,10-phenanthroline hydrate functionalized N-heterocyclic carbene and tetranuclear copper compound and preparation method for same | UNIV WUHAN TEXTILE | 2012-06-13 | — | — | CN | disclosed |