Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777298 | 0.90 | GABRA5 (0.63) | GABRA5ENPP2 | |
| SCHEMBL2926224 | 0.85 | ENPP2 (0.66) | GABRA5ENPP2 | |
| SCHEMBL1778130 | 0.83 | GABRA5 (0.72) | GABRA5ENPP2 | |
| SCHEMBL1778670 | 0.81 | ENPP2 (0.68) | GABRA5ENPP2 | |
| SCHEMBL1778131 | 0.80 | ENPP2 (0.67) | GABRA5ENPP2 | |
| SCHEMBL1777862 | 0.79 | GABRA5 (0.75) | GABRA5ENPP2 | |
| SCHEMBL1775811 | 0.79 | GABRA5 (0.66) | GABRA5ENPP2 | |
| SCHEMBL1778260 | 0.79 | GABRA5 (0.73) | GABRA5ENPP2 | |
| SCHEMBL1776603 | 0.79 | GABRA5 (0.69) | GABRA5ENPP2 | |
| SCHEMBL1777356 | 0.79 | GABRA5 (0.73) | GABRA5ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943619-B2 | Isoxazolo-pyridazine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-05-17 | — | — | US | disclosed |