Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.50 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475389 | 0.85 | L3MBTL1 (0.73) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL56875 | 0.85 | L3MBTL1 (0.73) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL423891 | 0.83 | L3MBTL1 (0.71) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL5391424 | 0.81 | L3MBTL1 (0.59) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL8066981 | 0.80 | LMNA (0.82) | L3MBTL1LMNABACE1CYP1A2HTT | |
| SCHEMBL15483502 | 0.79 | L3MBTL1 (0.56) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL8273082 | 0.79 | L3MBTL1 (0.56) | L3MBTL1LMNABACE1CYP1A2HTT | |
| SCHEMBL11352364 | 0.77 | L3MBTL1 (0.55) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL3094768 | 0.75 | BACE1 (1.00) | L3MBTL1LMNABACE1CYP1A2NPFFR1 | |
| SCHEMBL27661669 | 0.75 | CYP1A2 (0.64) | L3MBTL1LMNABACE1CYP1A2NPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353390-B2 | Genetically engineered microbes and methods for producing 4-hydroxycoumarin | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-05-31 | — | — | US | disclosed |